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randomized trials might be related to 1) lack of knowledge by treating clinicians, 2) obvious errors in routine practice encounters, or 3) decision-making for complex cases that have not been included in the existing RCTs

10.1007/s00404-019-05058-3 Arch Gynecol Obstet

For example, EGCG can be oxidatively metabolized by CYP450 enzymes (Zhao et al., 2019), while quercetin undergoes glucuronidation by uridine 5-diphospho-glucuronosyltransferase 1A1 to form quercetin-3-glucuronide, which can re-enter systemic circulation via enterohepatic recycling (Zhang et al., 2020)

As aforementioned, green tea contains multiple compounds with antioxidant properties, the most important of which are catechins, or tea flavonoids

Naringenin, a flavonoid found in citrus, is metabolized and excreted in both free and conjugated forms, showcasing its antioxidant properties