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According to this study, the mechanism would entail a disturbance of iron homeostasis, which would lead to a build-up of lipid ROS and subsequently improve sorafenib's therapeutic efficacy

Over time, the plaque becomes stable, a fibrous cap is formed, and the lesion can become hemodynamically significant resulting in a mismatch between myocardial oxygen demand and supply

Because cancer growth is dependent on angiogenesis, any compound that promotes this process could theoretically accelerate tumour growth

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Rates of change of pons and middle cerebellar peduncle diameters are diagnostic of multiple system atrophy of the cerebellar type