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Conclusion and perspectives BBB is a natural barrier protecting the brain from the entrance of toxins and pathogens

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Pharm Biol 61(1):11751185 Zhang C, Zhou J, Zhuo L, Zhang W, Lv L, Zhu L et al (2024) The TLR4/NF-B/NLRP3 and Nrf2/HO-1 pathways mediate the neuroprotective effects of alkaloids extracted from Uncaria rhynchophylla in Parkinsons disease

In the oligotrophic environment of the drinking water microbiome, these genes, along with those encoding for proteins related to cofactor and vitamin metabolism, might contribute to the survival of the bacteriophages hosts or enhance viral replication

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