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Activity modification during the healing phase allows tissue repair without constant re-injury

Neuroinflammation inhibition by small-molecule targeting USP7 noncatalytic domain for neurodegenerative disease therapy

This roughly mirrors the trial schedule used in the Phase 2 and Phase 3 studies

All Human Mouse Rat Cavia Rabbit Simian Canine Porcine Bovine Caprine Multi-species Pan-species Others Sample Type Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids Test Method Competitive Inhibition Assay Length 2h Detection Range 1.23-100ug/mL Sensitivity The minimum detectable dose of this kit is typically less than 0.52ug/mL

Dhillon 2017