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Wei L, Wen XS, Xian CJ

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Several clinical biomarkers have been helpful in investigating the degree of oxidative stress in CKD, but their clinical application remains to be further investigated

331 Notably, histone Kla has been identified to regulate NASH pathogenesis by facilitating the transcription of genes driving ferroptosis, such as ATF3, ATF4, and CHAC1, thereby promoting hepatocyte ferroptosis