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Oral collagen peptides: 10 to 15 grams daily to provide raw materials for connective tissue repair

Lack of specific preclinical disease models The in vitro BBB models, as well as disease models that exist today, are poorly predictive tools

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As the identified di-, hexa- and decadepsipeptides are not in line with the proposed biosynthetic assembly of three ready-made tetradepsipeptides 8,9 , these findings prompted us to ask whether the candidate depsipeptide esters are released from chemically unstable NRPS-bound PCP- S -ester or TE- O -ester intermediates of cereulide biosynthesis upon transesterification with ethanol, or are formed as artifacts by esterification of free depsipeptides or as cereulide degradation products released upon ethanolysis