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In multivariable models further adjusted for other potential confounders, only the quartile 3 group showed a significant reduction in mortality (HR=0.72, 95% CI: 0.57-0.91, P =0.005) ( Table 2 )

Although there is a positive trend in the use of vitamin B 12 for diabetic neuropathy, evidence is insufficient because most of the research trials lacked adequate follow-up periods or sample sizes and did not have a placebo arm for comparison

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After this initial period, your treatment will depend on whether the cause of your vitamin B12 deficiency is related to your diet or whether the deficiency is causing any neurological problems, such as problems with thinking, memory and behaviour