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The sublingual route ensures that glutathione is delivered directly into the bloodstream, bypassing the gastrointestinal system where it may be broken down, which could render it less effective

approximately 90% of cases are primary and occur de novo in elderly patients, whereas secondary cases progress from lower-grade astrocytoma, and are more prevalent in younger patients

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Phase I and pharmacokinetic study of elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, in adults with refractory hematological malignancies

doi: 10.1016/j.jcmgh.2019.04.008 499 LuniaMKSharmaBCSharmaPSachdevaSSrivastavaS