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paliurus exhibited antidiabetic and antiinflammatory effects through interaction with PIK3CA, increment of insulin expression, and modulation of gene expression related to the PI3K-AKT signaling pathway [50]

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Statistical Methods The per-allele odds ratio (relative risk) of the rare allele (105V, 114V, GSTM3*B ) was compared between cases and controls by assigning scores of 0, 1, and 2 to common homozygote, heterozygote, and rare homozygote, respectively, and calculating odds ratios per unit score by logistic regression