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If leg cramps began or worsened after a dose increase, discuss with your provider whether temporarily maintaining the current dose longer before further escalation might allow your body more time to adjust

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[852] Chronic glucocorticoid use among rheumatoid arthritis patients is associated with a higher health care costs due to increased occurrence of adverse events (for example, developing diabetes or osteoporosis, cardiovascular events such as thrombotic stroke, myocardial infarction, or death)

However, its important to understand that food only affects absorption rate, not elimination rate

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