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Accordingly, several gut metabolic dysfunctions could contribute to long-term neuro-cognitive impairments in PASC, including: (i) perturbed gut-brain axis due to loss of SCFA producing intestinal flora, which may cause neuropsychiatric disorders 728

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DOI: 10.1371/journal.pone.0035054 9

It usually forms heterodimeric complexes with its partner transcription factors to bind to DNA and regulate gene expression 131