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Description

Liver Int 40 , 13781394 (2020)

and because they are secretagogues, they amplify endogenous production rather than suppressing it

MYB proto-oncogene, transcription factor (MYB)-mediated expression of cysteine dioxygenase type 1 (CDO1), an enzyme that converts cysteine to taurine by catalyzing the oxidation of cysteine to sulfinic acid, can promote erastin-induced death in gastric cancer cells, 89 indicating that non-GSH-dependent cysteine metabolism is also involved in controlling ferroptosis