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Green R, Allen LH, Bjrke-Monsen A-L, et al

Antimicrobial polymers: the potential replacement of existing antibiotics

Radiother Oncol 79:231238

however, clinical treatment still faces numerous challenges: 30%-40% of patients exhibit primary or secondary non-response to existing therapeutic regimens such as biologics and small-molecule drugs, and prolonged administration tends to induce significant side effects

Serious adverse effects of extended-release niacin/laropiprant: results from the Heart Protection Study 2-Treatment of HDL to Reduce the Incidence of Vascular Events (HPS2-THRIVE) Trial