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A meta-analysis of metformin use during pregnancy for the treatment of diabetes mellitus combined with PCOS showed that early exposure to metformin does not increase the risk of fetal birth defects (Paschou et al., 2024)

Increased oxidative stress in prepubertal severely obese children: Effect of a dietary restriction-weight loss program

Nowadays, the distinctness between eryptosis and necroptosis of erythrocytes has been firmly established, and it can be assumed that erythrocytes have a branched cell death network

Herein, we summarise and discuss current information on the role of glycometabolic enzymes in promoting glucose metabolism and MDR in tumor cells (Figure 2), and conclude the molecular mechanisms by which glycometabolic enzymes promote MDR in tumor cells (Table 1)

Furthermore, co-morbid deficiencies in Nrf2 signaling and FXN suppresses the normal antioxidant response needed to deal with the continued oxidative stress (Paupe et al., 2009)