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The fatty acid modification Tirzepatide C20 fatty diacid modification at position 20 is critical for its extended half-life

It is used in laboratory settings to dilute or reconstitute research compounds while inhibiting bacterial growth in the solution

Sun X., et al

Chemical modification Various chemical modification methods have been introduced with the continuous progress of chemical synthesis and modification technologies to provide more precise treatments

Human safety data is insufficient to make any definitive statement about long-term use, with no large-scale toxicology or long-term safety trials in humans performed as of this writing