BPC-157 (Body Protection Compound-157), also designated as PL 14736, is a synthetic pentadecapeptide composed of 15 amino acids (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) that was first isolated and identified from human gastric juice in the early 1990s
The biodegradable, hydrophobic A polymer block comprises a polyester or poly(ortho ester), in which the polyester is synthesized from monomers selected from the group consisting of D,L-lactide, D-lactide, L-lactide, D,L-lactic acid, D-lactic acid, L-lactic acid, glycolide, glycolic acid, -caprolactone, -hydroxyhexanoic acid, -butyrolactone, -hydroxybutyric acid, -valerolactone, -hydroxyvaleric acid, hydroxybutyric acids, malic acid, and copolymers thereof and having an average molecular weight of between about 600 and 3000 Daltons
Morgenroth reported nanogel-based carrier for the intracellular delivery of radiophamaceuticals to brain tumor cells by functionalization of ligands of diphtheria toxin receptor overexpressed in abnormal cerebral blood vessels
It encodes the receptor for the ligand HGF
This allows moisture to transition directly from solid to vapor, leaving behind a dry, stable compound in the form of a light, crystalline powder
