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It is also the parent compound of its own structural class, the substituted amphetamines, [note 5] which includes prominent substances such as bupropion, cathinone, MDMA, and methamphetamine

Kampmann M (2024) Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases

Molecules, 19 (11), 17154-17172

Upon ingestion, it undergoes extensive hepatic and intestinal metabolism, yielding bioactive metabolites such as tetrahydrocurcumin, hexahydrocurcumin, and octahydrocurcumin, which retain biological activities comparable to the parent compound (25)