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This paper presents probably the best genome-wide association study with respect to ALD, demonstrating three important gene loci for risk

10.1038/nrc.2016.81 52 YeJ.FanJ.VennetiS.WanY

The results demonstrate that DBD significantly protects against oxidative stress through synergistic multitarget and multipathway effects, helps restore cellular homeostasis, and effectively inhibits the aging process