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These data suggest that oral GSH can replete GSH concentrations in several tissues following GSH depletion, such as after toxicologic or pathologic conditions that alter GSH homeostasis

In addition, in sorting rounds 4 and 5 of the second pathway, two reactions were performed in parallel: labeling in the absence or presence of low-concentration quenchers to prevent transcellular labeling

However, AEOL series has shown to have better stability (are excreted unchanged in the urine) and oral bioavailability compared to the EUK series, which can suffer from toxicity and instability under certain conditions (Liang et al., 2007

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37 , 38 , 39 Partial indirect support for this is that G6PD deficiency in Sardinia is more common at sea level compared to higher elevations, and this also parallels the endemicity of malaria