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Does anyone have any hard evidence that B12 vials really deteriorate after the use by date, or is it just a marketing game

Another reason for using the IM route is that some medicines may be irritating to fatty tissue under the skin or may be absorbed too slowly there

Think of it like this: if your research protocol calls for a 250 microgram (mcg) dose, but your reconstitution math is off by 20%, you're not actually administering 250mcg

Worsening insulin resistance drives higher insulin levels

We tailor the treatment regimen based on several factors such as the severity of the deficiency, the patients overall health condition, and their capacity to absorb Vitamin B12