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Many patients report that these withdrawal-like symptoms are not fully discussed before prescribing, leaving them unprepared for the challenges that may arise when attempting to reduce or stop the medication

Most of the clinical literature supporting the molecules covered here was generated using either topical-only application or in-office injection or microneedling

3.3 3D models of lipedema To overcome the limitations of 2D cultures, researchers have developed 3D cell culture models, such as spheroids, that better recapitulate the in vivo microenvironment and enable controlled experimental perturbations

The fluorescence microscope was then employed to observe the apoptosis of the cells

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