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Heavy drinkers with depressive symptoms typically exhibit (1) later age of MDD onset (post-25 years), (2) predominance of somatic symptoms (e.g., fatigue, insomnia) over cognitive rumination, and (3) partial responsiveness to selective serotonin reuptake inhibitors (SSRIs), which may reflect underlying serotonergic deficits compounded by ethanols neurotoxic effects (Pedrelli et al

Overall, DSIP emerges as a biologically significant peptide with broad medical promise

Emanuel, B

As the substance stops free radicals that not only damage our tissue and cells, but also destroy the collagen fibres responsible for skin elasticity, it could almost be described as a fountain of youth

The role of gaba in islet function