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The potential for publication bias and the exclusion of non-English articles may also impact the comprehensiveness of the findings

Additionally, healthy cells are susceptible to cytotoxic agent-induced pyroptosis due to the extensive expression of gasdermins in normal tissues [224]

Consequently, this leads to increased vasoconstriction, inflammation, and remodeling of resistant arteries

Cells were then cultured for additional 72 hours and either left untreated or triggered for 2 minutes with 10 M of substance P with or without prior treatment with the desired inhibitors

Over 13 years of research and development, a total of 22 Chinese invention patents, 1 utility model patent, and 2 international invention patents have been applied for