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As was pointed out, there is no toxicity without protein binding but there can be protein binding without toxicity [39]

Mitochondrial proteins Consistent with proteomic data (Supplementary Fig

Gut dysbiosis and reactive oxygen species (ROS)-induced oxidative stress contribute to the accumulation of -syn, which subsequently propagates to the brain via the vagus nerve, thereby establishing a gut-brain axis mechanism in disease progression (Soni et al., 2024)

Han R, Wan J, Han X, Ren H, Falck JR, Munnuri S, et al

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