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In silico analysis identified Glo1 as the only druggable target upregulated after trabectedin treatment and correlated with poor prognosis

A sub-chronic toxicity study involving mice treated with thymoquinone at 30, 60, and 90 mg/kg/day showed no signs of toxicity or death (681)

Post-translational activation of GCL by dimercaprol in cultured BV-2 microglia prevents LPS-induced production of proinflammatory cytokines and iNOS induction (McElroy et al., 2017a)

This review provides an updated, mechanistic evaluation of these developments, with particular emphasis on how defined structural attributes influence antimicrobial activity, organelle-specific targeting, and integrated imaging-therapy platforms

Avoid fatty, greasy, and spicy foods during the initial titration weeks