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Lactoferrin: an important host defence against microbial and viral attack

The functional expansion of Nrf2 in proliferating cells directs the enhancement of anabolic metabolism, maintains redox homeostasis and further promotes the activation of PI3KAkt signaling, suggesting the presence of positive feedback between Nrf2 and the PI3KAkt pathway in proliferating cells (Figure 9)

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Quercetin mitigates sepsis-induced renal injury via inhibiting inflammatory and oxidative pathways in mice

However, it upregulated NOS protein expression in endothelial and neuronal cells, maintaining mitochondrial energetics [21]