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Smith EA, Macfarlane GT

49 Moreover, administration of high doses of IL-1 fails to exacerbate APAP-induced liver injury, further suggesting a limited role of IL-1 signaling in the pathogenesis of APAP hepatotoxicity

For this reason, make sure to avoid vitamin B12-fortified foods that are sold or stored in clear containers or plastic bags (10)

Because the active transport system is saturable, absorption will be less efficient at higher concentrations of intake, but the intake levels at which absorptive efficiency decreases in humans are not known