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Amitriptyline can have also anticholinergic, arrhythmogenic, and behavioral side effects, thus it can cause constipation, dry mouth, sedation, QT prolongation, increased appetite

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The same review also lists some supplements that may work to chelate heavy metals from the body: Glutathione: Certain forms of glutathionemay protect cells from the oxidative damage that heavy metals can cause

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10.1001/jamapsychiatry.2013.3080 JAMA Psychiatry 251 ZanierE.BertaniI.SammaliE.PischiuttaF.ChiaravallotiM.VeglianteG.et al (2018)