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mRNA was extracted from tissue homogenates of the hippocampus and cerebral cortex of rmTBI and control groups (n = 4 per group at 48 h or 90 days after injury) using the phenol-chloroform method ( 2.9 Statistical analyses An a priori power analysis used of 0.05, power of 0.8, and means and SD from previous laboratory data, and determined that eight mice per group were required for cognitive and neurological tests

Other cell death mechanisms In lung cancer research, in addition to the cell death mechanisms mentioned above, various other forms of cell death induced by TCMs have been investigated, including necroptosis [121, 199], DNA damage [200, 201], immunogenic cell death [223, 241, 242] and cellular senescence [72, 72]

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Progress should be tracked with symptoms and function changes

Biomarker analyses in the phase III ASCENT study of sacituzumab govitecan versus chemotherapy in patients with metastatic triple-negative breast cancer