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BPC-157 is not FDA-approved for medical use and is classified as a research peptide

J Bacteriol 176:37493756

suggested that ketamine may cause degeneration of neuromuscular junctions and/or proprioceptive sensory fibers in the course of chronic addiction and the mechanisms of ketamine-induced cystitis are related to a loss of nerve fibers among the muscles of the bladder and a decline in choline acetyltransferase (a marker for cholinergic neurons) [184]