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Thus, they genetically engineered CD28 CAR-T cells to express PD-1 dominant negative receptor (DNR), to overcome PD-1-mediated immunosuppression in a single administration

Pharmaceutics 15:2704 Lee SK, Ha ES, Park H, Jeong JS, Kim JS, Baek Ih, Yoon IS, Yun H, Yoo JW, Moon HR, Kim MS (2023b) Synergistic solvation effect and modeling of itraconazole solubility in eight binary mixtures (dichloromethane and chloroform + primary alcohol) at the range of 288.15 K to 308.15 K

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Also, animal models that represent the normotensive subset of glaucoma such as impaired glutamate transporters and transgenic optineurin E50K or TBK1 mice may help in understanding neuroprotective and neurorestorative processes upon IOP-independent mechanisms of RGC apoptosis (Harada et al., 2019)

Camarero J