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For example, SYN DA -treated microglia only increased the expression of glutathione-S-transferase ( GSTA ) 60-fold while the response to misfolded SYN was a 500-fold increase in gene expression

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Moreover, riboflavin deficiency is reported associated with impaired maintenance of mucous membranes and low grade bowel inflammation (78, 79) which could well contribute to the malabsorption of nutrients such as B6, zinc, and folate (80)

Such plant-based screening allows the simplified and controllable identification of regulatory nodes, particularly those linked to Ca 2+ and NO signalling, which are often difficult to dissect functionally in mammalian systems

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