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Preparation of a nanovaccine against Brucella melitensis M16 based on PLGA nanoparticles and oligopolysaccharide antigen

Front Cardiovasc Med

Over the course of the three developmental ages, Escherichia coli lipopolysaccharides-induced nitrite levels in macrophages (increased nitric oxide synthase activity) ranged from 60 to 278 microM in the basal diet group, but they were significantly higher in all Spirulina dietary groups (0.5% group range = 198 to 457 microM