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16 This commercial software utilizes an extensive database derived from the Human Metabolome Database (HMDB), 17 which accounts for changes in pH

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Yet, these factors have not been fully characterized to elucidate the molecular mechanisms underlying sexual dimorphism in the liver during health and disease (251)

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C-PC improved CDDP efficacy in U87 cells compared to CDDP alone but failed to affect cytotoxicity in U87-EGFRvIII cells, suggesting that C-PC as a standalone therapy is preferred for targeting resistant GBM subtypes