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Description

There is insufficient safety data for either compound during pregnancy, and animal studies with GLP-1 agonists showed adverse fetal effects

In particular, there was no significant rise in Cho and decrease in NAA peak, no reversal of the tNAA/tCho ratio, and no notable lactate or lipid peak

Materials and methods Animal experiments C57BL/6J aged (20 months) male mice and mast cell deficient c-Kit wsh /cKit wsh mice (12 months) were housed in a specific pathogen-free facility (light cycle 12/12 h light/dark)