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We apply our functional genomics platforms to systematically identify genetic modifiers of levels of reactive oxygen species and peroxidized lipids, and neuronal survival under oxidative stress, one of the predominant stresses in aging 6 and neurodegenerative diseases 7

A survey of two dozen studies showed that B12 can be an effective treatment for peripheral neuropathy for both short-term pain relief and longer-term nerve regeneration

Hsp90 induces Acsl4-dependent glioma ferroptosis via dephosphorylating Ser637 at Drp1

Nutu et al., 2013a