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Acetonitrile (10 mM ammonium bicarbonate (95:5, v/v) was used as mobile phase A and acetonitrile (10 mM ammonium bicarbonate (5:95, v/v) was used as mobile phase B

Traditional hot-water extraction provides high levels of the immune-modulating beta-glucans and related polysaccharides, while the mycelial biomass contains the full spectrum of active metabolites from the mycelium and young fruiting body of the mushroom, including other beta-glucans and extra-cellular polysaccharides, phytosterols (including ergosterol (provitamin D2), proteins, lipids and arabinoxylans. MycoNutri products are manufactured in the U K to EC food standards The mycelial biomass used is grown in the USA on sterile grain-based substrate and is optimized to maximise substrate conversion and production of secondary metabolites such as eritadenine. All MycoNutri products are suitable for vegetarians and vegans (capsules are of plant origin) No additives are used and the products are dairy, gluten, maize and soya-free Organically certified by The Soil Association. 60 x 500mg vcaps

PS exposure was similar in these two media, perhaps due to cells reaching a plateau in PS exposure capacity (as suggested by the time-course analysis, Figures 3C, D )

doi: 10.3389/fncel.2024.1408364, 21 ChuJ.LiJ.SunL.WeiJ

Similar to natural drugs, many synthetic drugs have properties that enhance the GSH system and thus protect cells from oxidative damage