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Fibromyalgia, irritable bowel syndrome, migraines, chemical sensitivity, frequent miscarriage and frequent blood clots are all conditions associated with MTHFR anomaly

3.6.3.2 Microbial metabolites A substantial body of research highlights the role of gut microbiota and their metabolites, particularly SCFAs, in regulating metabolic, endocrine, and immune functions, with emerging evidence pointing to their involvement in neuro-immunoendocrine pathways through the MGBA (Silva et al., 2020)

Similarly, Arg catabolism is coupled with the urea cycle to produce bioactive metabolites such as polyamines to support T cell proliferation and differentiation 10,11,12

Immunotherapies targeting -syn aggregates offer new hope for disease-modifying treatment in PD

Unlike other vertebrate models, using light-sheet microscopy, the whole-brain activity of larval zebrafish can be rapidly obtained without attaching any fiber optic cables (Ahrens et al., 2013)