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The concept of selective insulin resistance is therefore critical for understanding the complex pathophysiology of T2DM, in which the insulin resistant state prevails in many tissues, but in a tissue-dependent, pathway-specific manner

Common signs include: Persistent fatigue or weakness Pale or slightly yellow skin Shortness of breath Tingling or numbness in the hands and feet Difficulty with memory or concentration In more advanced cases, neurological symptoms may become more pronounced

Folic acid (vitamin B9) is the synthetic form of folate used in supplements and fortified foods

Both unborn and newborn babies have a special need for vitamin B12 and if the mother is a vegetarian or a vegan, this need may not be met either through her diet for the unborn or through her breast milk for the newborn