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For example, HF individuals with reduced ejection fraction are generally advised against participating in competitive sports, while those with HF and preserved ejection fraction, classified as low-risk, may engage in certain competitive activities

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*Correspondence: Mohanned Naif Alhussien, [email protected] These authors share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The challenge now is to integrate this new knowledge and explore how it can be used to categorize patients by molecular phenotype and tailor treatment more effectively

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