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Methods: All eligible, and consenting individuals with MASLD were prospectively enrolled at an academic center in the US from July 2017-Jan 2024 (N = 991), who completed Rapid Eating Assessment for Participants (REAP) (N=815), and beverage questionnaire (N=801)

Protocols lasting 812 weeks show measurably better tissue outcomes when injection timing aligns with researcher workflow patterns that ensure zero missed doses, compared to theoretically optimal but inconvenient schedules that introduce gaps