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But what does this mean for those in the lab

doi: 10.1152/ajpcell.00632.2004

Mutations in these enzymes underscore their developmental importance: Alkbh5 knockout female mice have impaired fertility owing to defective RNA metabolism in germ cells 139 , and loss-of-function mutations in FTO in mice cause growth retardation, abnormalities in brain and cardiac development, and increased perinatal lethality 140,141,142,143