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Freezing can damage the peptide structure just as much as shaking

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4 Several important issues in the study of RIBE Up to now, a number of studies have attempted to demonstrate the mechanisms underlying RIBE and some specific biological molecules involved have been identified, however, there are still some issues in RIBE to be resolved, which are important to both a better understanding of RIBE and the practical modulation of RIBE in the fields of radiotherapy and radioprotection