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Glia pathology in the prefrontal cortex in alcohol dependence with and without depressive symptoms

As the central nervous system becomes increasingly impaired, these critical functions dont receive the required signals from the brain, and they begin to shut down

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Endogenous PRLMs are structurally unstable, rapidly metabolized, and possess short half-lives in vivo, limiting their direct application as therapeutic agents

These findings support the hypothesis that pyroptosis may be involved in melanocyte death associated with ROS in vitiligo [12, 60]