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Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration

Additionally, Nrf2 , activated by oxidative stress, enhances NOS3 transcription by upregulating antioxidant response elements in the NOS3 promoter (Wu et al., 2019)

Yet the two afflictions have much in common and often the same amyloids play a role in both

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This led us to the possibility that inhibition was occurring through adduct formation, followed by inhibitory action of the adduct