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Importantly, the beneficial effects of metformin have been confirmed via a post-hoc pooled analysis, demonstrating its potential in improving SLE disease activity and decreasing flare risks, particularly in serologically quiescent SLE patients (171)

Les donnes prcliniques documentent des effets sur les tendons (Achille, MCL, rotulien), les muscles, la peau (cicatrisation cutane), les os, les nerfs priphriques, le tractus gastro-intestinal (ulcres, colites) et le tissu cardiaque

The ASQ-3 is an easily administered checklist of developmental status standardised for children aged 166 months.35 The screening system includes age-appropriate questionnaires for every 2/3-month intervals

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Sodium nitroprusside (SNP)-induced NO-mediated relaxation was significantly reduced by tetraethylammonium (TEA), a K+ channel blocker, compared to controls