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Annals of the New York Academy of Sciences , 2007

doi: 10.2217/fvl-2016-0110 [DOI] [Google Scholar] 8

Bast, Adverse fooddrug interactions, Regul

Figure 6 4.1 Ferroptosis and DN The pathogenesis of DN involves multiple factors, including dysregulation of glucose and lipid metabolism, oxidative stress, accumulation of advanced glycation end-products (AGEs), inflammation, activation of the innate immune system, genetic susceptibility, activation of the renin-angiotensin system, and miRNAs (112114)

Consequently, this review systematically assesses the research on the therapeutic potential of GA across various stages of ASCVD progression, pointing out that GA is a promising drug candidate applied in the prevention and treatment of ASCVD