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Obtaining it outside a supervised research context carries product-quality and legal risks that sit outside any benefit-risk calculation based on efficacy data alone

(2024) found that double mutants with attenuated MT synthesis exhibited salt sensitivity, and the transcriptome analysis showed that the expression of a large number of salt-responsive genes was affected by SNAT defects, which were associated with IAA biosynthesis and various signaling pathways

E.BrianM.CarrellR

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Several MAT2A inhibitors have been identified, and three have progressed into clinical trials for the treatment of MTAP-deficient solid tumors or lymphomas 25