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Vitamin B12 significantly impacts the synthesis of energy and the development of red blood cells

Individuals with severe B12 deficiency benefit most from IV infusions because intravenous delivery raises serum levels faster than other supplementation routes

Because B12 is found almost exclusively in animal foods, the NIH notes that vegans and vegetarians face a higher risk of deficiency without supplementation

The onset of conditions like Polioencephalomalacia (Goat Polio) can disrupt thiamine production in the rumen, leading to metabolic slowdown, cell death, and brain swelling