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Energy Metabolism of Cancer: Glycolysis Versus Oxidative Phosphorylation (Review)

174,175 Several oncogenic mechanisms, such as the transcription factor HIF-1, PI3K/Akt/mTOR pathway and c-Myc, upregulate genes encoding glucose transporters and glycolytic proteins, including GLUT1, GLUT3, and lactate dehydrogenase (LDH)

Main Research Findings 1) Intra-articular administration of AOD9604 was shown to improve cartilage regeneration in cases of collagenase-induced knee osteoarthritis

It cuts into skin, divides cells, and can cause profuse bleeding